TLR7 antibody (10R-1016)

Mouse monoclonal TLR7 antibody

Synonyms Monoclonal TLR7 antibody, Anti-TLR7 antibody, UNQ248 antibody, PRO285 antibody, TLR-7, TLR-7 antibody, toll-like receptor 7 antibody, TLR 7 antibody, TLR7, tlr 7 antibody, TLR 7
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen TLR7 antibody was raised in mouse using recombinant human TLR7 (451-500aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 4F4
Isotype IgG1 kappa
Source Anti-human TLR7 antibody, clone 4F4, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TLR7 protein.
Method of Purification TLR7 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TLR7 is one of the toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing conserved microbial structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.

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Availability: In stock

Price: €249.33
Size: 100 ul
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