Immunohistochemical staining using TMEFF2 antibody (10R-7209)
Immunohistochemical analysis of TMEFF2 protein in paraffin embedded Adenocarcinoma of Human endometrium tissue using TMEFF2 antibody
TMEFF2 antibody
Immunohistochemical staining using TMEFF2 antibody (10R-7209)
Immunohistochemical analysis of TMEFF2 protein in paraffin embedded Adenocarcinoma of Human endometrium tissue using TMEFF2 antibody
Western Blot analysis using TMEFF2 antibody (10R-7209)
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TMEFF2 protein (Right) or empty vector (Left) detected with TMEFF2 antibody
Specifications
Host
Mouse
Clone
1B4
Isotype
IgG2a
Method of Purification
TMEFF2 antibody was purified by affinity chromatography.
Form & Buffer
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
TMEFF2, a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor?like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERk1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region.