TNF alpha antibody (10R-6647)
Mouse monoclonal TNF alpha antibody
Overview
Overview
| Synonyms | Monoclonal TNF alpha antibody, Anti-TNF alpha antibody, TNF-alpha antibody, TNFa TNF-a antibody, TNF-alpha antibody, Tumor Necrosis Factor alpha antibody, Anti TNF alpha antibody, Tumor Necrosis Factor alpha antibody, TNF alpha antibody, TNFa TNF-a antibody |
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| Specificity | Human |
| Applications | FC, Functional Assay, IHC, IP, WB |
| Assay Information | It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest |
Specifications
| Host | Mouse |
|---|---|
| Clone | MAb1 |
| Isotype | IgG1 kappa |
| Method of Purification | TNF alpha antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | The MAb1 antibody reacts with human tumor necrosis factor- alpha, a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4 T cells. TNF- alpha has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF- alpha forms dimers and trimers and also exists as a 26 kDa membrane bound form. |
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