TNFR1 antibody (70R-13806)
Affinity purified Rabbit polyclonal TNFR1 antibody
Overview
Overview
| Synonyms | Polyclonal TNFR1 antibody, Anti-TNFR1 antibody, TNF-R55 antibody, tumor necrosis factor receptor superfamily, p55-R antibody, TNF-R-I antibody, p60 antibody, MGC19588 antibody, TNFR-1, TNFR1, TNFR55 antibody, TNFR 1 antibody, CD120a antibody, p55 antibody, NFRSF1A antibody, TNFR 1, TNF-R antibody, member 1A antibody, TBP1 antibody, FPF antibody, TNFR-1 antibody, TNFR60 antibody, TNFAR antibody |
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| Applications | IHC-P, WB |
| Immunogen | TNFR1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human TNFR1 as the immunogen |
Images
Western Blot analysis using TNFR1 antibody (70R-13806)
Lane 1: Recombinant Human TNFR1 Protein 10ng; Lane 2: Recombinant Human TNFR1 Protein 5ng; Lane 3: Recombinant Human TNFR1 Protein 2.5ng
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | TNFR1 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | TNFR1 is the receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNFRSF1A contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
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