TNFRSF10C antibody (70R-10454)
Affinity purified rabbit polyclonal TNFRSF10C antibody
Overview
Overview
| Synonyms | Polyclonal TNFRSF10C antibody, Anti-TNFRSF10C antibody, TNFRSFC-10 antibody, LIT antibody, TNFRSFC 10, DCR1 antibody, TRID antibody, CD263 antibody, MGC149502 antibody, TNFRSFC 10 antibody, MGC149501 antibody, tumor necrosis factor receptor superfamily, decoy without an intracellular domain antibody, member 10c, TNFRSF10C, TRAILR3 antibody, TNFRSFC-10 |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | TNFRSF10C antibody was raised in rabbit using the N terminal of TNFRSF10C as the immunogen |
| Assay Information | TNFRSF10C Blocking Peptide, catalog no. 33R-5730, is also available for use as a blocking control in assays to test for specificity of this TNFRSF10C antibody |
Images
Western Blot analysis using TNFRSF10C antibody (70R-10454)
TNFRSF10C antibody (70R-10454) used at 0.2-1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
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| Form & Buffer | Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | TNFRSF10C is the receptor for the cytotoxic ligand TRAIL. TNFRSF10C lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. TNFRSF10C may protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. |
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