TNFRSF13B protein (His tag) (80R-2693)
Purified recombinant TNFRSF13B protein (His tag)
|Synonyms||Tumor necrosis factor receptor superfamily member 13B protein, CD267 protein, CVID protein, CVID2 protein, TACI protein, TNFRSF14B protein, TNFRSF13B, TNFRSF-13B, TNFRSF 13B, TNFRSF-13B protein, TNFRSF 13B protein|
SDS-PAGE analysis of TNFRSF13B protein (His tag) (80R-2693)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-165 aa: MGSSHHHHHH SSGLVPRGSH MGSMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYS|
|Grade & Purity||> 90% pure|
|Molecular Weight||20.9 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||TNFRSF13B, also known as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). It was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family. It controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. Recombinant human TNFRSF13B protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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