Tollip antibody (10R-1116)

Mouse monoclonal Tollip antibody

Synonyms Monoclonal Tollip antibody, Anti-Tollip antibody, Tollip antibody, Toll interacting protein antibody, Anti Tollip antibody , IL-1RAcPIP antibody, IL-1RAcPIP antibody, Toll interacting protein antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen Tollip antibody was raised in mouse using recombinant human Tollip (61-274aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone k1B17
Isotype IgG2a kappa
Source Anti-human Tollip antibody, clone k1B17, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Tollip protein.
Method of Purification Tollip antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors(TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.

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Availability: In stock

Price: €249.33
Size: 100 ul
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