Topoisomerase II antibody (10R-T116a)

Mouse monoclonal Topoisomerase II antibody

Synonyms Monoclonal Topoisomerase II antibody, Anti-Topoisomerase II antibody, Anti Topoisomerase II antibody, Topoisomerase II alpha antibody, Topoisomerase II antibody, Topoisomerase II alpha antibody, Topoisomerase II beta antibody, Topoisomerase II beta antibody
Specificity Human
Cross Reactivity Mouse, rat
Applications WB
Immunogen Topoisomerase II antibody was raised in mouse using recombinant human DNA-topoisomerase IIa (N-terminal fragment) as the immunogen.

Specifications

Host Mouse
Clone AK5
Isotype IgG1
Method of Purification Topoisomerase II antibody was purified by affinity chromatography.
Form & Buffer PBS, pH7.2, with 50% glycerol.

Usage & Assay Information

Usage Recommendations WB: 5-10 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Type II topoisomerases cut both strands of the DNA helix simultaneously in order to unwind it. The energy required for this is the hydrolysis of ATP, unlike type I topoisomerase, which is thermodynamically favored. In this process, these enzymes change the linking number of circular DNA by +/-2.

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Availability: In stock

Price: €500.53
Size: 100 ug
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