TP53I3 protein (His tag) (80R-1336)
Purified recombinant Human TP53I3 protein
|Synonyms||TP53I3, quinone oxidoreductase homolog protein, TP53I3 protein, TPI3 53 protein, Putative quinone oxidoreductase protein, PIG3 protein, TPI3-53 protein, TPI3 53, TPI3-53, Tumor protein p53 inducible protein 3., Quinone oxidoreductase PIG3 p53 induced gene 3 protein protein|
Coomassie Blue stained SDS-PAGE of TP53I3 protein (His tag) (80R-1336)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-332 amino acids: MGSSHHHHHH SSGLVPRGSH MLAVHFDKPG GPENLYVKEV AKPSPGEGEV LLKVAASALN RADLMQRQGQ YDPPPGASNI LGLEASGHVA ELGPGCQGHW KIGDTAMALL PGGGQAQYVT VPEGLLMPIP EGLTLTQAAA IPEAWLTAFQ LLHLVGNVQA GDYVLIHAGL SGVGTAAIQL TRMAGAIPLV TAGSQKKLQM AEKLGAAAGF NYKKEDFSEA TLKFTKGAGV NLILDCIGGS YWEKNVNCLA LDGRWVLYGL MGGGDINGPL FSKLLFKRGS LITSLLRSRD NKYKQMLVNA FTEQILPHFS TEGPQRLLPV LDRIYPVTEI QEAHKYMEAN KNIGKIVLEL PQ|
|Grade & Purity||> 90% pure|
|Molecular Weight||37.6 kDa (352aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||TP53I3, also known as quinone oxidoreductase PIG3, is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. It is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. This protein has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Recombinant human TP53I3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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