TPO protein (30R-2579)
Purified recombinant Human TPO protein
Overview
Overview
| Synonyms | Myeloproliferative leukemia virus oncogene ligand protein, Megakaryocyte growth and development factor protein, MGC163194 protein, TPO protein, THPO protein, MGDF protein, Megakaryocyte colony-stimulating factor protein, ML protein, MPLLG protein, MKCSF protein, C-mpl ligand protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
|---|---|
| Grade & Purity | > 98% pure |
| Method of Purification | TPO protein was purified using a a proprietary chromatographic technique. |
| Form & Buffer | Supplied in lyophilized form with no additives |
Usage & Assay Information
| Bioactivity | The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found < 1 ng/ml, corresponding to a specific activity of > 1 x 10^6 IU/mg |
|---|
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|---|
| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | TPO stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product