TRAIL antibody (10R-T140A)

Mouse monoclonal TRAIL antibody

Synonyms Monoclonal TRAIL antibody, Anti-TRAIL antibody, Anti TRAIL antibody, TL2 antibody, TNFSF10 antibody, TNFSF10 antibody, TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNF-related apoptosis-inducing Ligand antibody, TL2 antibody
Specificity Human TRAIL
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.

Specifications

Host Mouse
Clone M912292
Isotype IgG1 kappa
Molecular Weight 20.0 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS.

Usage & Assay Information

Usage Recommendations ELISA: 2-4 ug/ml, Inhibition: 0.3-0.6 ug/ml, WB: 0.25-0.5 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic ?death domain?, which activates the cell?s apoptotic machinery.

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Availability: In stock

Price: €211.69
Size: 500 ug
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