TRAIL Receptor 2 antibody (20R-TR048)
Rabbit polyclonal TRAIL Receptor 2 antibody
Overview
Overview
| Synonyms | Polyclonal TRAIL Receptor 2 antibody, Anti-TRAIL Receptor 2 antibody, KILER antibody, TRAIL Receptor-2 antibody, TNFRSF10B antibody, soluble TRAIL Receptor-2 antibody, TRICKB antibody, TRAIL R2 antibody, DR5 antibody, TRICK2A antibody, TRAIL R2 antibody |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | User optimized |
| Immunogen | TRAIL receptor 2 antibody was raised in rabbit using N terminus of the human TRAIL-R2 protein as the immunogen. |
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Form & Buffer | Serum containing 0.02% Sodium Azide. |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R2 is widely expressed and the gene encoding TRAIL-R2 is located on human chromosome 8p22-21. TRAIL-R2 engages a caspase-dependent apoptotic pathway but, in contrast to TRAIL-R1, TRAIL-R2 mediates apoptosis via the intracellular adaptor molecule FADD/MORT1. |
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