Transferrin protein (30R-3085)
Purified native Human Transferrin protein
Overview
Overview
| Synonyms | Serotransferrin protein, Beta-1 metal-binding globulin protein, Siderophilin protein |
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| Species | Human |
| Protein Type | Native |
| Applications | ELISA, SDS-PAGE, WB |
Specifications
| Source | plasma |
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| Grade & Purity | > 90% pure |
| Form & Buffer | Supplied in liquid form in PBS buffer |
Storage & Safety
| Storage | Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles |
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| Biohazard Information | Raw materials ethically sourced from healthy donors, however, this product has NOT been tested for infectious diseases. Please handle as potentially hazardous, with full laboratory safety precautions. |
General Information
| Biological Significance | Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. |
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