Transferrin protein (HRP) (65C-CH0930)
PurifiedNative Human Transferrin protein (HRP)
Overview
Overview
| Synonyms | TF protein, beta 1 metal binding globulin protein, Siderophilin protein, Apotransferrin protein, Serotransferrin precursor protein, DKFZp781D0156 protein, PRO2086 protein, PRO1400 protein, PRO1557 protein |
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| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human serum |
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| Method of Purification | Transferrin protein (HRP) was purified by selective precipitation and tandem chromatography followed by dialysis. |
| Tag/Conjugate | HRP |
| Form & Buffer | Lyophilized from 0.02M K3PO4, pH 7.2, with 0.15M NaCl, 10 mg/ml BSA, and 0.01% gentamicin sulfate. DO NOT add NaN3. Immunoglobulin and protease free. |
Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. |
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