Treponema pallidum p15 protein (30R-AT065)
Purified recombinant Treponema pallidum p15 protein
Overview
Overview
| Synonyms | T. pallidum p15 protein |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Residues | The E.Coli derived recombinant protein is fused at N-terminus with GST tag and contains the Trp. Pallidum p15 immunodominant regions. |
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| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Treponema pallidum p15 protein was purified by a proprietary chromatographic technique. |
| Tag/Conjugate | GST tag |
| Form & Buffer | 70 mM tris-HCl, pH 8.0, with 84mM NaCl, 14mM Glutathione, 30% Glycerol and 0.2% Sarcosil. Please Note: Buffer may change with new Lots. |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue. |
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