Treponema pallidum TmpA protein (80-1396)

Purified recombinant Treponema pallidum TmpA protein

Synonyms T. pallidum TmpA protein, Treponema pallidum TmpA antigen, TmpA protein, Treponema pallidum protein
Species Viral
Protein Type Recombinant
Applications SDS-PAGE

Images

Western blotanalysis of Treponema pallidum TmpA protein (80-1396)

Western blot using anti-his antibody to detect the purified his-tagged TmpA protein.

Specifications

Residues 1-345 aa (full length) with N-terminal His tag and Thioredoxin
Expression System E.coli
Grade & Purity > 95% pure
Method of Purification Treponema pallidum TmpA protein was purified in a native conformation by affinity, ion exchange, and size exclusion chromatography
Molecular Weight 55 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in 50mM Tris pH 8.5 / 150mM NaCl / 10 glycerol /1mM EDTA and 2mM DTT
Concentration 1 mg/ml

Storage & Safety

Storage Aliquot and store at -20 deg C

General Information

Biological Significance Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.

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Images

  • Western blotanalysis of Treponema pallidum TmpA protein (80-1396) | Western blot using anti-his antibody to detect the purified his-tagged TmpA protein.

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