Treponema pallidum TmpA protein (80-1396)
Purified recombinant Treponema pallidum TmpA protein
Overview
Overview
| Synonyms | T. pallidum TmpA protein, Treponema pallidum TmpA antigen, TmpA protein, Treponema pallidum protein |
|---|---|
| Species | Viral |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
Western blotanalysis of Treponema pallidum TmpA protein (80-1396)
Western blot using anti-his antibody to detect the purified his-tagged TmpA protein.
Specifications
| Residues | 1-345 aa (full length) with N-terminal His tag and Thioredoxin |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Treponema pallidum TmpA protein was purified in a native conformation by affinity, ion exchange, and size exclusion chromatography |
| Molecular Weight | 55 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in 50mM Tris pH 8.5 / 150mM NaCl / 10 glycerol /1mM EDTA and 2mM DTT |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Aliquot and store at -20 deg C |
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General Information
| Biological Significance | Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue. |
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