TRIM23 antibody (70R-12484)
Affinity purified Rabbit polyclonal TRIM23 antibody
Overview
Overview
| Synonyms | Polyclonal TRIM23 antibody, Anti-TRIM23 antibody, E3 ubiquitin-protein ligase TRIM23 antibody, TRIM-23, ARFD1 antibody, TRIM 23 antibody, TRIM23 antibody, tripartite motif containing 23 antibody, tripartite motif-containing 23 antibody, RING finger protein 46 antibody, ARD1 antibody, GTP-binding protein ARD-1 antibody, ARF domain protein 1 antibody, TRIM-23 antibody, ADP-ribosylation factor domain protein 1 64kDa antibody, tripartite motif protein TRIM23 antibody, TRIM 23, RNF46 antibody, TRIM23, tripartite motif-containing protein 23 antibody, ADP-ribosylation factor domain-containing protein 1 antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | TRIM23 antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 1 and 44 of TRIM23 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | TRIM23 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 64 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. |
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