Immunofluorescent staining using TRIM37 antibody (70R-12976)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TRIM37 antibody at 1:200 dilution.
TRIM37 antibody
Immunofluorescent staining using TRIM37 antibody (70R-12976)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TRIM37 antibody at 1:200 dilution.
Western blot analysis using TRIM37 antibody (70R-12976)
Western blot analysis of 30 ug of whole cell lysate (A: A431; B: HeLa; C: HepG2) using a 7.5 % SDS PAGE gel and TRIM37 antibody at a dilution of 1:1000
Immunohistochemical staining using TRIM37 antibody (70R-12976)
Immunohistochemical staining of paraffin-embedded U87 xenograft using TRIM37 antibody at a dilution of 1:500
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
TRIM37 antibody was purified by antigen-affinity chromatography
Molecular Weight
108 kDa
Form & Buffer
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.