TrkA antibody (70R-11686)

Rabbit polyclonal TrkA antibody

Synonyms Polyclonal TrkA antibody, anti-TrkA antibody, Trk-A antibody, CIPA antibody, NTRK1 antibody, TRK1 antibody, TRK antibody
Cross Reactivity Human, Mouse, Rat
Applications IHC, IP, WB
Immunogen TrkA antibody was raised in Rabbit using synthetic peptide surrounding amino acid 494 of human TrkA as the immunogen.
Assay Information TrkA Blocking Peptide, catalog no. 33R-10666, is also available for use as a blocking control in assays to test for specificity of this TrkA antibody

Images

Western Blot analysis using TrkA antibody (70R-11686)

Western blot analysis of TrkA expression using Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates.

Specifications

Host Rabbit
Isotype IgG
Method of Purification TrkA antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.5-4 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TrkA, the high affinity Nerve Growth Factor receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using TrkA antibody (70R-11686)</font></div>     | Western blot analysis of TrkA expression using Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates.

Availability: In stock

Price: €282.21
Size: 100 ug
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