Troponin I antibody (cardiac) (10-1359)
Mouse monoclonal Troponin I antibody
Overview
Overview
| Synonyms | Monoclonal Troponin I antibody, Anti-Troponin I antibody, Troponin 1 antibody |
|---|---|
| Applications | ELISA, Lateral Flow |
| Immunogen | Troponin I antibody (cardiac) was raised in Mouse using cardiac Troponin I as the immunogen |
| Assay Information | This antibody can be used as the labelling antibody with 10-1360 as the coating antibody to detect Troponin I |
Specifications
| Host | Mouse |
|---|---|
| Clone | M1709TI1 |
| Isotype | IgG1 |
| Grade & Purity | > 95% pure |
| Form & Buffer | Supplied in 50mM NaCl, 10 mM PBS pH 8.0, with 0.05% NaN3 |
Storage & Safety
| Storage | Store at 2-8 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
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Troponin I antibody
Mouse monoclonal Troponin I antibody