Troponin I antibody (Cardiac) (10-T79C)
Mouse monoclonal Troponin I antibody (Cardiac)
Overview
Overview
| Synonyms | Monoclonal Troponin I antibody (Cardiac), Anti-Troponin I antibody (Cardiac) |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | ELISA, IHC, IP, WB |
| Immunogen | Troponin I antibody (Cardiac) was raised in mouse using animo acid residues 41-49 of cTnI as the immunogen. |
| Assay Information | 10-T79C can be used in a sandwich immunoassay as a coating antibody in conjunction with 10-T79J as the conjugate antibody. Alternatively, 10-7965, 10-T79F, or 10-T79Hcan be used in a sandwich immunoassay as a coating antibody in conjunction with 10-T79C as the conjugate antibody. |
Specifications
| Host | Mouse |
|---|---|
| Clone | M805142 |
| Isotype | IgG2b |
| Method of Purification | Troponin I antibody (Cardiac) was purified by chromatography on protein A Sepharose. |
| Form & Buffer | Protein A purified IgG supplied in PBS, pH 7.4, 0.1 % NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
|---|
Storage & Safety
| Storage | Store at 4 deg C. |
|---|---|
| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. cTnI molecule contains two serines in the 22 and 23 positions. Both amino acid residues can be phosphorylated in vivo by protein kinase A, so four forms of protein – one dephospho, two monophospho and one bisphospho – can coexist in the cell. |
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