This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. This product contains sodium azide as preservative. Although the amount of sodium azide is very small ap
General Information
Biological Significance
Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.