Troponin I protein (30-1232)

Purified native Human Troponin I protein

Synonyms Cardiac-specific troponin I protein, cTnl protein, Troponin I protein, TnI protein
Species Human
Protein Type Native

Specifications

Source Human Heart
Grade & Purity > 95% pure
Molecular Weight 24 kDa
Form & Buffer 8M Urea, 50mM Tris-HCl, 15mM beta-mercaptoethanol, 1mM EDTA
Concentration 100 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short term storage. For long term storage aliquot and store at -20 deg C

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

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Availability: In stock

Price: €261.76
Size: 25 ug
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