Troponin I protein (Skeletal Muscle) (Chicken) (30-1019)
Purified native Chicken Troponin I protein (Skeletal Muscle)
Overview
Overview
| Synonyms | Troponin I protein, Skeletal Muscle Troponin I protein, TnI protein, Skeletal-specific troponin I protein, sTnl protein |
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| Species | Chicken |
| Protein Type | Native |
Specifications
| Source | Skeletal Muscle |
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| Grade & Purity | > 95% pure |
| Method of Purification | Troponin I protein was purified by Tn-C affinity chromatography. |
| Molecular Weight | 22 kDa |
| Form & Buffer | Supplied in 8M Urea, 100 mM NaCl, 50 mM Tris.HCl, 1 mM EDTA, 15 mM beta-mercaptoethanol, pH 7.8 |
| Concentration | 0.25 - 2.0 mg/mL |
Storage & Safety
| Storage | Store at -25 deg C or below. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. |
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