Troponin I Type 1 Blocking Peptide (33R-7266)
A synthetic peptide for use as a blocking control in assays to test for specificity of TNNI1 antibody, catalog no. 70R-1250
Overview
Overview
| Synonyms | Troponin I Type 1 control peptide, Troponin I Type 1 antibody Blocking Peptide, Anti-Troponin I Type 1 Blocking Peptide, DKFZp451O223 Blocking Peptide, SSTNI Blocking Peptide, TNN1 Blocking Peptide, TNNI1 Blocking Peptide |
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| Protein Type | Synthetic |
| Applications | IHC, WB |
Specifications
| Residues | PPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGD |
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| Molecular Weight | 21 kDa |
| Form & Buffer | Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml. |
Storage & Safety
| Storage | Store at -20 deg C long term. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. |
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