TRPV4 antibody (70R-5164)

Rabbit polyclonal TRPV4 antibody raised against the middle region of TRPV4

Synonyms Polyclonal TRPV4 antibody, Anti-TRPV4 antibody, TRP12 antibody, Transient Receptor Potential Cation Channel Subfamily V Member 4 antibody, TRPV-4 antibody, TRPV 4 antibody, TRPV-4, VRL-2 antibody, OTRPC4 antibody, TRPV4, TRPV 4, VRL2 antibody, VR-OAC antibody, VROAC antibody
Specificity TRPV4 antibody was raised against the middle region of TRPV4
Cross Reactivity Human
Applications WB
Immunogen TRPV4 antibody was raised using the middle region of TRPV4 corresponding to a region with amino acids RVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPR
Assay Information TRPV4 Blocking Peptide, catalog no. 33R-8239, is also available for use as a blocking control in assays to test for specificity of this TRPV4 antibody

Images

Western Blot analysis using TRPV4 antibody (70R-5164)

TRPV4 antibody (70R-5164) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 91 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of TRPV4 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance TRPV4 is a non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation of TRPV4 by exposure to hypotonicity within the physiological range exhibits an outward rectification. TRPV4 also activated by low pH, citrate and phorbol esters and increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.

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Images

  • Western Blot analysis using TRPV4 antibody (70R-5164) | TRPV4 antibody (70R-5164) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: €285.10
Size: 50 ug
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