TSH alpha protein (30-AT20P)
Highly purified native Human TSH alpha protein
Overview
Overview
| Synonyms | Thyroid Stimulation Hormone protein, Thyroid Stimulating Hormone alpha protein, Thyrotropin alpha subunit protein |
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| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human pituitary glands |
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| Grade & Purity | Highly pure |
| Form & Buffer | Supplied as a lyophilized powder |
Usage & Assay Information
| Bioactivity | Immunopotency: 0.9 wt/wt |
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Storage & Safety
| Storage | Store at 4 deg C for short term and at -20 deg C for longer periods |
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| Contaminants | hTSH beta: 0.019%; hFSH beta: 0.003%; hLH beta: 0.050% |
| Biohazard Information | No FDA testing information, handle as if infectious |
General Information
| Biological Significance | Thyroid stimulating hormone (TSH) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid gland. TSH is a glycoprotein that consists of alpha and beta subunits. The alpha subunit is thought to be the effector region responsible for stimulation of adenylate cyclase (involved the generation of cAMP). The beta subunit (TSHB) is unique to TSH, and therefore determines its receptor specificity. |
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