Immunofluorescent staining using TULP3 antibody (10R-7229)
Immunofluorescent staining of COS7 cells transiently transfected with recombinant TULP3 protein using TULP3 antibody
TULP3 antibody
Immunofluorescent staining using TULP3 antibody (10R-7229)
Immunofluorescent staining of COS7 cells transiently transfected with recombinant TULP3 protein using TULP3 antibody
Western Blot analysis using TULP3 antibody (10R-7229)
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TULP3 protein (Right) or empty vector (Left) detected with TULP3 antibody
Immunohistochemical staining using TULP3 antibody (10R-7229)
Immunohistochemical analysis of TULP3 protein in paraffin embedded Adenocarcinoma of Human ovary tissue using TULP3 antibody
Specifications
Host
Mouse
Clone
4E5
Isotype
IgG1
Method of Purification
TULP3 antibody was purified by affinity chromatography.
Form & Buffer
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function.