UBCH2 protein (His tag) (80R-2537)

Purified recombinant Human UBCH2 protein (His-tag)

Synonyms UBCH2, UBCH 2 protein, UBCH-2 protein, UBCH-2, UBCH 2, Ubiquitin conjugating enzyme 2 protein, UBCH2 protein, Ubiquitin conjugating enzyme protein
Species Human
Protein Type Recombinant

Specifications

Expression System E.coli
Method of Purification UBCH2 protein was purified using a a proprietary chromatographic technique.
Molecular Weight 22.2 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT

Storage & Safety

Storage Store at -80 deg C

General Information

Biological Significance UBCH2 is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBCH2 consists of two functionally independent domains, an N-terminal core domain with ubiquitin conjugating activity, and a C-terminal domain that interacts with substrate proteins. This protein is useful for in vitro ubiquitinylation reactions. The His-tagged version of this enzyme is not susceptible to self-ubiquitinylation, which can occur with GST-tagged versions.

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Price: €572.60
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