UBCH5a protein (His tag) (80R-2539)
Purified recombinant Human UBCH5a protein (His-tag)
Overview
Overview
| Synonyms | UBCHa 5 protein, Ubiquitin conjugating enzyme protein, UBCHa 5, UBCH5a protein, UBCHa-5 protein, UBCH5a, Ubiquitin conjugating enzyme H5a protein, UBCHa-5 |
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| Species | Human |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Method of Purification | UBCH5a protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 17.0 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied at a concentration of 1.0 mg/ml in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT |
Storage & Safety
| Storage | Store at -80 deg C |
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General Information
| Biological Significance | UBCH5a is highly homologous to the S. cerevisiae UBC4/5 family of E2 enzymes demonstrated to be essential for degradation of regulatory and abnormal proteins. UBCH5a, together with UBCH5b and UBCH5c, are the most active class of E2 enzymes in cell extracts and are associated with regulation of a number of transcription factors. Specifically, UBCH5a stimulates the conjugation of ubiquitin to the tumor suppressor p532. Useful for in vitro ubiquitinylation reactions. |
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