UBCH5b protein (His tag) (80R-2540)
Purified recombinant Human UBCH5b protein (His-tag)
Overview
Overview
| Synonyms | UBCH5b, UBCHb-5 protein, Ubiquitin conjugating enzyme H5b protein, UBCHb 5, UBCH5b protein, UBCHb 5 protein, UBCHb-5, Ubiquitin conjugating enzyme protein |
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| Species | Human |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Method of Purification | UBCH5b protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 17.0 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied at a concentration of 1.0 mg/ml in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT |
Storage & Safety
| Storage | Store at -80 deg C |
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General Information
| Biological Significance | UBCH5b is highly homologous to the S. cerevisiae UBC4/5 family of E2 enzymes, demonstrated to be essential for degradation of regulatory and abnormal proteins. UBCH5b, together with UBCH5a and UBCH5c, are the most active class of E2 enzymes in cell extracts and are associated with regulation of a number of transcription factors including p53. Useful for in vitro ubiquitinylation reactions. |
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