UBE2V2 protein (His tag) (80R-1404)
Purified recombinant Human UBE2V2 protein
|Synonyms||Ubiquitin-conjugating enzyme E2 variant 2, UBEV-2 protein, EDAF-1 protein, EDPF-1 protein, MMS2 protein, EDPF1 protein, UBEV-2, UBE2V2, DDVIT1 protein, UEV-2 protein, DDVit-1 protein, UBEV 2 protein, UBEV 2, UEV2 protein|
Coomassie Blue stained SDS-PAGE of UBE2V2 protein (His tag) (80R-1404)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-145 amino acids: MGSSHHHHHH SSGLVPRGSH MAVSTGVKVP RNFRLLEELE EGQKGVGDGT VSWGLEDDED MTLTRWTGMI IGPPRTNYEN RIYSLKVECG PKYPEAPPSV RFVTKINMNG INNSSGMVDA RSIPVLAKWQ NSYSIKVVLQ ELRRLMMSKE NMKLPQPPEG QTYNN|
|Grade & Purity||> 95% pure|
|Molecular Weight||18.5 kDa (165aa) confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||UBE2V2, also known as ubiquitin-conjugating enzyme E2 variant 2, constitutes a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. This protein also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. Recombinant human UBE2V2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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