Ubiquilin 1 antibody (70R-13429)

Affinity purified Rabbit polyclonal Ubiquilin 1 antibody

Synonyms Polyclonal Ubiquilin 1 antibody, Anti-Ubiquilin 1 antibody, Ubiquilin -1 antibody, UBQLN1 antibody, FLJ90054 antibody, Ubiquilin 1, Ubiquilin 1 antibody, hPLIC-1 antibody, Ubiquilin 1, protein linking IAP with cytoskeleton 1 antibody, Ubiquilin -1, ubiquilin 1 antibody, DSK2 antibody, ubiquilin-1 antibody, DA41 antibody, PLIC-1 antibody, UBQN antibody, XDRP1 antibody
Cross Reactivity Human
Applications ICC, IF, WB

Images

Immunofluorescent staining using Ubiquilin 1 antibody (70R-13429)

Immunofluorescence analysis of paraformaldehyde-fixed A549, using Ubiquilin-1 antibody at 1:200 dilution.

Specifications

Host Rabbit
Isotype IgG
Method of Purification Ubiquilin 1 antibody was purified by antigen-affinity chromatography
Molecular Weight 63 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:200, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes an ubiquitin-like protein that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease.

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Images

  • <div><font face=Calibri size=2>Immunofluorescent staining using Ubiquilin 1 antibody (70R-13429)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed A549, using Ubiquilin-1 antibody at 1:200 dilution.
  • <div><font face=Calibri size=2>Western blot analysis using Ubiquilin 1 antibody (70R-13429)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: 293T) using a 7.5 % SDS PAGE gel and Ubiquilin 1 antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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