UBLCP1 protein (80R-4202)
Recombinant Human UBLCP1 protein with His tag
Overview
Overview
| Synonyms | Human UBLCP1 protein, Recombinant UBLCP1 protein, Ubiquitin-like domain-containing CTD phosphatase 1 protein, CPUB1 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | Control, SDS-PAGE |
Images
Coomassie blue stained SDS-PAGE showing analysis of UBLCP1 protein(80R-4202)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 1-318 amino acids of Human UBLCP1 protein: MGSSHHHHHH SSGLVPRGSH MGSMALPIIV KWGGQEYSVT TLSEDDTVLD LKQFLKTLTG VLPERQKLLG LKVKGKPAEN DVKLGALKLK PNTKIMMMGT REESLEDVLG PPPDNDDVVN DFDIEDEVVE VENREENLLK ISRRVKEYKV EILNPPREGK KLLVLDVDYT LFDHRSCAET GVELMRPYLH EFLTSAYEDY DIVIWSATNM KWIEAKMKEL GVSTNANYKI TFMLDSAAMI TVHTPRRGLI DVKPLGVIWG KFSEFYSKKN TIMFDDIGRN FLMNPQNGLK IRPFMKAHLN RDKDKELLKL TQYLKEIAKL DDFLDLNHKY WERYLSKKQG Q |
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| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 39.2 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) containing 10% glycerol and 1mM DTT |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles. |
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General Information
| Biological Significance | UBLCP1 also known as ubiquitin-like domain-containing CTD phosphatase 1. This protein dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome. Recombinant human UBLCP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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