UCHL1 antibody (20R-UG001)

Goat polyclonal UCHL1 antibody

Synonyms Polyclonal UCHL1 antibody, Anti-UCHL1 antibody, UCHL-1, UCHL 1 antibody, UCHL-1 antibody, Ubinquitin C-terminal Hydrolase L1 antibody, UCHL 1, UCHL1
Specificity Human UCHL1
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen UCHL1 antibody was raised in goat using a peptide; NFRKKQIEELKGQEVSPK, as the immunogen.

Specifications

Host Goat
Form & Buffer Whole serum, supplied as a liquid without preservative.

Usage & Assay Information

Usage Recommendations ELISA: >1:71,350, WB: >1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Ubiquitin carboxyl-terminal hydrolase L1 (UCH ?L1) is one of the most abundant proteins in the brain and represents 1-2% of total soluble brain proteins. UCH-L1 activity is thought to cleave polymeric ubiquitin to monomers and to hydrolyze bonds between ubiquitin-protein conjugatges to regenerate ubiquitin monomers. In many degenerative diseases, ubiquitin has been identified as a component of several inclusion bodies and certain of these are associated with UCH-L1 activity. One such inclusion is the Lewy body of Parkinson?s disease. Since a polymorphism has been detected in the UCH-L1 gene, it is suspected to have a role is some forms of Parkinson?s disease.

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Availability: In stock

Price: €140.19
Size: 250 ul
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