UCP4 antibody was purified by affinity chromatography.
Form & Buffer
Affinity purified IgG lyophilized from 100mM Tris, pH 7.5, with 0.02% BSA, and 0.05% NaN3. Reconstitute in water to a concentration of 1 mg/ml. Do not dilute further until ready to use.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. UCP4 (mouse/rat 322 aa; human 323 aa; chromosome 6p11.2-q12) is expressed in both fetal and adult brain tissues.