UNG antibody (10R-7235)
Mouse monoclonal UNG antibody
Overview
Overview
| Synonyms | Monoclonal UNG antibody, Anti-UNG antibody, DGU antibody, DKFZp781L1143 antibody, HIGM4 antibody, UDG antibody, UNG1 antibody, UNG15 antibody, UNG2 antibody, Monoclonal UNG antibody, Anti-UNG antibody, DGU antibody, DKFZp781L1143 antibody, HIGM4 antibody, UDG antibody, UNG1 antibody, UNG15 antibody, UNG2 antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | UNG antibody was raised in Mouse using full length human recombinant protein of human UNG produced in HEK293T cell as the immunogen. |
Images
Western Blot analysis using UNG antibody (10R-7235)
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant UNG protein (Right) or empty vector (Left) detected with UNG antibody
Specifications
| Host | Mouse |
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| Clone | 1A6 |
| Isotype | IgG1 |
| Method of Purification | UNG antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 0.5-1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1:2000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. |
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