VAMP8 protein (His tag) (80R-1081)
Purified recombinant Human VAMP8 protein
|Synonyms||Vesicle-associated membrane protein 8 protein, VAMP8 protein, VAMP-8, VAMP8, VAMP 8 protein, VAMP-8 protein, Endobrevin protein, EDB protein, VAMP-8 protein, Vesicle associated membrane protein 8., VAMP 8 protein, VAMP5 protein, Vesicle-associated membrane protein 8 VAMP 5 protein, VAMP 8|
Coomassie Blue stained SDS-PAGE of VAMP8 protein (His tag) (80R-1081)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-76 amino acids: MGSSHHHHHH SSGLVPRGSH MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKM|
|Grade & Purity||> 85% pure|
|Molecular Weight||10.9 kDa (96aa), confirmed by MALDI-TOF.|
|Form & Buffer||Liquid in 20mM Tris pH8.0, 0.1mM PMSF, 0.2M NaCl, 50% glycerol|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Vehicle-associated membrane (VAMP8) ,also known as endobrevin, is the main component of a SNARE complex involved in the docking and fusion of synaptic vesicles with the presynaptic membrane. This protein plays a role in regulated enzyme secretion in pancreatic acinar cells and is involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. It is required for dense-granule secretion in platelets. Recombinant VAMP8 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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