VASP antibody (10R-7236)

Mouse monoclonal VASP antibody

Synonyms Monoclonal VASP antibody, Anti-VASP antibody, Vasodilator-stimulated phosphoprotein antibody, Monoclonal VASP antibody, Anti-VASP antibody, Vasodilator-stimulated phosphoprotein antibody
Cross Reactivity Human, Dog
Applications IHC, WB
Immunogen VASP antibody was raised in Mouse using full length human recombinant protein of human VASP produced in HEK293T cell as the immunogen.

Images

Immunohistochemical staining using VASP antibody (10R-7236)

Immunohistochemical analysis of VASP protein in paraffin embedded Carcinoma of Human liver tissue using VASP antibody

Specifications

Host Mouse
Clone 1F3
Isotype IgG1
Method of Purification VASP antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5-1 mg/ml

Usage & Assay Information

Usage Recommendations IHC: 1:150, WB: 1:200-500

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions.

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Images

  • Immunohistochemical staining using VASP antibody (10R-7236) | Immunohistochemical analysis of VASP protein in paraffin embedded Carcinoma of Human liver tissue using VASP antibody
  • Western Blot analysis using VASP antibody (10R-7236) | Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant VASP protein (Right) or empty vector (Left) detected with VASP antibody

Availability: In stock

Price: €323.11
Size: 100 ul
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