Immunohistochemical staining using VASP antibody (10R-7236)
Immunohistochemical analysis of VASP protein in paraffin embedded Carcinoma of Human liver tissue using VASP antibody
VASP antibody
Immunohistochemical staining using VASP antibody (10R-7236)
Immunohistochemical analysis of VASP protein in paraffin embedded Carcinoma of Human liver tissue using VASP antibody
Western Blot analysis using VASP antibody (10R-7236)
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant VASP protein (Right) or empty vector (Left) detected with VASP antibody
Specifications
Host
Mouse
Clone
1F3
Isotype
IgG1
Method of Purification
VASP antibody was purified by affinity chromatography.
Form & Buffer
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions.