VEGF165 protein (30R-2288)
Purified recombinant Human VEGF165 protein
Overview
Overview
| Synonyms | Vascular Endothelial Growth Factor protein, Folliculostellate cell-derived growth factor protein, VPF protein, Glioma-derived endothelial cell mitogen protein, VEGF-165 protein |
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| Species | Human |
| Protein Type | Recombinant |
Specifications
| Residues | aa 27-191 |
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| Expression System | HEK293 cells |
| Grade & Purity | > 95% pure |
| Molecular Weight | 19.2 kDa |
| Form & Buffer | Supplied in lyophilized form from a 0.2 um filtered solution in PBS buffer, pH 7.2, with BSA as a carrier protein. |
Storage & Safety
| Storage | Store at 2-8 deg C for short term storage. For Long term storage, aliquot and store at -20 deg C to -80 deg C. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <1.0 EU per 1 ug of the protein by the LAL method |
General Information
| Biological Significance | VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), kDaR gene product (the Mouse homolog of kDaR is the flk-1 gene product) and the flt4 gene product. |
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