Vesicular GABA Transporter antibody (20R-2578)

Rabbit polyclonal Vesicular GABA Transporter antibody

Synonyms Polyclonal Vesicular GABA Transporter antibody, Anti Vesicular GABA Transporter antibody, gamma-Aminobutyric acid receptor antibody
Specificity Human VGAT
Cross Reactivity Rat
Applications IF
Immunogen Vesicular GABA Transporter antibody was raised in rabbit using synthetic peptide from the C-terminus of human VGAT coupled to BSA as the immunogen.

Specifications

Host Rabbit
Form & Buffer Supplied in lyophilized form. Dissolve the antiserum in 50 - 100 ul distilled water and dilute further in 0.1 M PBS with 1% BSA and 0.1% Na-azide

Usage & Assay Information

Usage Recommendations IF: 1:1500 - 1:2500

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Gamma-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. In vertebrates, GABA acts at inhibitory synapses in the brain by binding to specific transmembrane receptors in the plasma membrane of both pre- and postsynaptic neuronal processes.

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