Vitronectin protein (30R-2452)
Purified native Human Vitronectin protein
Overview
Overview
| Synonyms | V75 protein, S protein, Serum-spreading factor protein |
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| Species | Human |
| Protein Type | Native |
Specifications
| Source | Human Plasma |
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| Method of Purification | Vitronectin protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 75 kDa |
| Form & Buffer | Supplied in lyophilized form from 10 mM sodium phosphate, pH 7.7 |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Vitronectin is a protein that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 ug/ml. |
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