Vitronectin protein (30R-2452)

Purified native Human Vitronectin protein

Synonyms V75 protein, S protein, Serum-spreading factor protein
Species Human
Protein Type Native

Specifications

Source Human Plasma
Method of Purification Vitronectin protein was purified using a a proprietary chromatographic technique.
Molecular Weight 75 kDa
Form & Buffer Supplied in lyophilized form from 10 mM sodium phosphate, pH 7.7

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Vitronectin is a protein that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 ug/ml.

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