West Nile Virus NS1 protein (80-1546)
Purified Recombinant West Nile Virus NS1 protein (His tag)
Overview
Overview
| Synonyms | West Nile Virus NS1 antigen, WNV NS1 antigen, WNV NS1 protein, WNV Nonstructural protein, West Nile Virus Nonstructural protein |
|---|---|
| Species | Viral |
| Protein Type | Recombinant |
Specifications
| Expression System | 293 cells |
|---|---|
| Grade & Purity | > 95% pure |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in DPBS, pH 7.4 |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at -80 deg C |
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General Information
| Product Use | West Nile Virus NS1 protein for use in the research laboratory |
|---|---|
| Biological Significance | The West Nile Virus NS1 protein is a native hexameric presentation. The hexamer is believed to be the biologically active form of NS1 involved in key aspects of West Nile Fever pathogenesis. The resultant West Nile Virus NS1 protein is purified to a high degree, is in its native folding state, and possesses all post-translational modifications. |
| Implications in Disease | The incubation period for WNV is typically from between 2 and 15 days. Headache can be a prominent symptom of WNV fever, meningitis, encephalitis, meningoencephalitis, and it may or may not be present in poliomyelitis-like syndrome. Thus, headache is not a useful indicator of neuroinvasive disease. Symptoms may include fever, headaches, fatigue, muscle pain or aches (myalgias), malaise, nausea, anorexia, vomiting, and rash. Less than 1% of the cases are severe and result in neurological disease when the central nervous system is affected. |
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