Wilms Tumor 1 antibody (70R-12541)
Affinity purified Rabbit polyclonal Wilms Tumor 1 antibody
Overview
Overview
| Synonyms | Polyclonal Wilms Tumor 1 antibody, Anti-Wilms Tumor 1 antibody, Wilms tumor 1 antibody, Wilms Tumor 1, WAGR antibody, GUD antibody, Wilms Tumor 1, WT33 antibody, AWT1 antibody, Wilms Tumor -1, NPHS4 antibody, WIT-2 antibody, amino-terminal domain of EWS|last three Zinc fingers of the DNA-binding domain of WT1 antibody, Wilms Tumor 1 antibody, Wilms Tumor -1 antibody, Wilms tumor protein antibody, WT1 antibody |
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| Cross Reactivity | Human, Rat |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | Wilms Tumor 1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 209 and 449 of Wilms Tumor 1 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | Wilms Tumor 1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 56 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.21 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:1000, ICC:1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. |
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