XIAP antibody (70R-14051)

Affinity purified Rabbit polyclonal Human XIAP antibody

Synonyms Polyclonal XIAP antibody, Anti-XIAP antibody, API3 antibody, BIRC4 antibody, Baculoviral IAP repeat-containing 4 antibody, ILP antibody, Apoptosis inhibitor 3 antibody, X-linked Inhibitor of Apoptosis antibody, IAP-like protein antibody, X-linked IAP antibody, XLP2 antibody
Applications IHC-P, WB
Immunogen XIAP antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human BIRC4, different from the related Rabbit sequence by two amino acids, as the immunogen

Images

Immunohistochemical staining using XIAP antibody (70R-14051)

Immunohistochemistry of paraffin embedded section of Human Intestinal Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification XIAP antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance IAP (inhibitor of apoptosis protein) is an evolutionarily conserved inhibitory factor of apoptosis. IAP directly binds to caspase which plays the central role in operation of apoptosis and inhibits it. Human XIAP (Xchromosomelinked inhibitor of apoptosis protein) is known as one of the IAP family and binds to caspase 3, 7, and 9 directly and inhibits their functions. XIAP has three BIR (baculovirus IAP repeat) domains. It is confirmed that BIR2 domain binds to caspase 3 and 7, and BIR3 domain binds to caspase 9. Also it is known that the RING finger domain has a ubiquitin ligase activity and is associated with ubiquitination of caspase.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunohistochemical staining using XIAP antibody (70R-14051) | Immunohistochemistry of paraffin embedded section of Human Intestinal Cancer Tissue
  • Western blot analysis using XIAP antibody (70R-14051) | Lane 1: SMMC Cell Lysate, Lane 2: HELA Cell Lysate, Lane 3: A431 Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
OR
Shipping
View Our Distributors