ZCCHC17 protein (His tag) (80R-1735)
Purified recombinant Human ZCCHC17 protein
|Synonyms||HSPC251 protein, zinc finger CCHC domain containing 17 protein, ZCCHC-17, ZCCHC 17, ZCCHC 17 protein, Nucleolar protein of 40 kDa protein, pNO40 protein, PS1D protein, putative S1 RNA-binding domain protein protein, ZCCHC-17 protein, RP11-266K22.1 protein, ZCCHC17|
Coomassie Blue stained SDS-PAGE of ZCCHC17 protein (His tag) (80R-1735)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-241 amino acids: MGSSHHHHHH SSGLVPRGSH MGSMNSGRPE TMENLPALYT IFQGEVAMVT DYGAFIKIPG CRKQGLVHRT HMSSCRVDKP SEIVDVGDKV WVKLIGREMK NDRIKVSLSM KVVNQGTGKD LDPNNVIIEQ EERRRRSFQD YTGQKITLEA VLNTTCKKCG CKGHFAKDCF MQPGGTKYSL IPDEEEEKEE AKSAEFEKPD PTRNPSRKRK KEKKKKKHRD RKSSDSDSSD SESDTGKRAR HTSKDSKAAK KKKKKKKHKK KHKE|
|Grade & Purity||> 90% pure|
|Molecular Weight||30.0 kDa (264aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 2mM DTT, 20% glycerol, 0.1M NaCl and 0.1mM PMSF.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||ZCCHC17, also known as pNO40 or PS1D, is a 241 amino acid protein that interacts with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. Recombinant human ZCCHC17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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