Zika virus envelope antibody (10-2714)

Mouse monoclonal Zika virus envelope antibody

Synonyms Zika ENV antibody, Zika virus E antibody, Zika envelope antibody, Zika antibody, Zika virus antigen, recombinant Zika antibody, recombinant Zika antigen, Zika virus envelope antigen, recombinant Zika envelope antibody, recombinant Zika envelope antigen, ZIKV antibody, ZIKV antigen, ZIKV envelope
Cross Reactivity No cross reactivity with recombinant Dengue and Chikungunya antigens
Applications ELISA, Lateral Flow
Immunogen Zika virus envelope antibody was raised in mouse using recombinant Zika envelope protein as the immunogen.
Assay Information Zika virus envelope protein, catalog no. 30-1932, was used as the immunogen for this antibody and can be used as a positive control.

Specifications

Host Mouse
Clone M86647
Isotype IgG1 kappa
Grade & Purity > 90% pure
Method of Purification Purified by DEAE column chromatography
Form & Buffer Supplied as liquid in 0.015M potassium phosphate, 0.85% NaCl, pH 7.2 with 0.05% sodium azide

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance Zika virus spreads to people primarily through the bite of an infected Aedes species mosquito, but it can also be sexually transmitted. ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-translationally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins. The E (envelope) protein composes the majority of the virion surface and is involved with aspects of replication such as host cell binding and membrane fusion.
Implications in Disease There is growing evidence that Zika virus infections may be linked to fetal and newborn microcephaly and serious neurological complications, such as Guillain–Barré syndrome. NS1 is the major antigenic marker for viral infection. To date, no clinically approved vaccines or therapeutics are available to prevent and control of Zika virus infection.

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Zika virus envelope protein

Recombinant Zika virus envelope protein

Availability: In stock

Price From: Price: €241.31
Price From: Price: €241.31
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