Zika virus envelope antibody (10-2715)
Mouse monoclonal Zika virus envelope antibody
Overview
Overview
| Synonyms | Zika ENV antibody, Zika virus E antibody, Zika envelope antibody, Zika antibody, Zika virus antigen, recombinant Zika antibody, recombinant Zika antigen, Zika virus envelope antigen, recombinant Zika envelope antibody, recombinant Zika envelope antigen, ZIKV antibody, ZIKV antigen, ZIKV envelope |
|---|---|
| Cross Reactivity | No cross reactivity with recombinant Dengue and Chikungunya antigens |
| Applications | ELISA, Lateral Flow |
| Immunogen | Zika virus envelope antibody was raised in mouse using recombinant Zika envelope protein as the immunogen. |
| Assay Information | Zika virus envelope protein, catalog no. 30-1932, was used as the immunogen for this antibody and can be used as a positive control. |
Specifications
| Host | Mouse |
|---|---|
| Clone | M86648 |
| Isotype | IgG1 kappa |
| Grade & Purity | > 90% pure |
| Method of Purification | Purified by DEAE column chromatography |
| Form & Buffer | Supplied as liquid in 0.015M potassium phosphate, 0.85% NaCl, pH 7.2 with 0.05% sodium azide |
Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | Zika virus disease is caused by a virus transmitted primarily by Aedes mosquitoes. This is the same mosquito that transmits dengue, chikungunya and yellow fever. It is a flavivirus that was first identified in Uganda in 1947 in monkeys through a network that monitored yellow fever. It was later identified in humans in 1952 in Uganda and the United Republic of Tanzania. The first large outbreak of disease caused by Zika infection was reported from the Island of Yap (Federated States of Micronesia) in 2007. In July 2015 Brazil reported an association between Zika virus infection and Guillain-Barré syndrome and later in 2015 Brazil reported an association between Zika virus infection and microcephaly. |
|---|---|
| Implications in Disease | Many people infected with Zika virus will have mild or no symptoms while others will have fever, rash, joint pain, or conjunctivitis. People rarely die from Zika virus. Pregnant woman can pass Zika virus to her fetus causing microcephaly and other severe fetal brain defects. |
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