Zika virus envelope protein (30-1935)

Recombinant Zika virus envelope protein

Synonyms Zika envelope protein, Zika protein, recombinant Zika envelope protein, ZIKV envelope, Zika ENV protein, Zika virus E protein, Zika virus antigen, recombinant Zika protein, recombinant Zika antigen, Zika virus envelope antigen, recombinant Zika envelope antigen, ZIKV protein, ZIKV antigen
Species Viral
Protein Type Recombinant
Applications ELISA, Lateral Flow, WB
Assay Information This protein binds to Zika converted human serum polyclonal antibodies and cross reacts with Dengue virus converted human serum polyclonal antibodies.

Specifications

Expression System E.coli
Grade & Purity > 95% pure
Method of Purification Purified by aqueous solvent extraction and preparative electrophoresis to > 95% purity
Molecular Weight 49 kDa
Form & Buffer Supplied as liquid in 50 mM NaCl, 50 mM NaPO4, pH 8.5 with 0.02% SDS

Usage & Assay Information

Usage Recommendations ELISA: 1-2 ug/ml protein range for titering Dengue virus converted human polyclonal antibodies. Lateral Flow: 1-2mg/ml (1-2ul/cm)

Storage & Safety

Storage Store in small aliquots at -70 deg C. Avoid repeated freeze thaw cycles.

General Information

Biological Significance Zika virus was first discovered in Ughanda in 1947 in monkeys infected by the virus through bites from of infected Aedes species mosquitos. Zika virus has become a highly researched disease due to increase in incidences from 2007 to 2016, when the virus spread eastward, across the Pacific Ocean to the Americas. In 2015–16 Zika virus epidemic reached pandemic levels. The Zika envelope protein composes the majority of the virion surface and it is involved with replication, such as host cell binding and membrane fusion.
Implications in Disease The symptoms of Zika infection vary from non-existant to visible rash, fever, headaches and conjunctivitis. It is usually non life threatening, but has been associated to microcephaly in unborn fetuses when passed by an infected pregnant mother.

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Availability: In stock

Price From: Price: €159.51
Price From: Price: €159.51
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